Research published February 5 in the Annals of Internal Medicine found that the most physically fit midlifers were nearly 40 percent less likely to develop dementia or Alzheimer’s disease by the time they were 65 compared with their counterparts who were not as in shape
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Research by van Praag et. al. has made it clear that regular, moderate intensity voluntary exercise confers a number of neuroprotective benefits across the life span. These include more and denser vascular and synaptic networks, higher levels of circulating neurotrophic (brain building) hormones and improved cognitive functions. Exercise also promotes retention of new hippocampal and cerebellar neurons, which are produced throughout the lifespan but go undifferentiated in underactive individuals. Interestingly, enriched environments (i.e. obstacle courses) play a key role in breaking the “ceiling” that seems to exist for research animals that only get running time without novel tasks or enriched environments.